Recommendations of the DNA Commission of the International Society for Forensic Genetics (ISFG) on short tandem repeat sequence nomenclature

• Published in: Forensic science international : genetics 2024-01, Vol.68, p.102946, Article 102946
• Main Authors: Gettings, Katherine B, Bodner, Martin, Borsuk, Lisa A, King, Jonathan L, Ballard, David, Parson, Walther, Benschop, Corina C G, Børsting, Claus, Budowle, Bruce, Butler, John M, van der Gaag, Kristiaan J, Gill, Peter, Gusmão, Leonor, Hares, Douglas R, Hoogenboom, Jerry, Irwin, Jodi, Prieto, Lourdes, Schneider, Peter M, Vennemann, Marielle, Phillips, Christopher
• Format: Article
• Language: English
• Subjects: Databases, Nucleic Acid; DNA Fingerprinting; Forensic Genetics - methods; Humans; Microsatellite Repeats; Societies, Scientific; Terminology as Topic
• ISSN: 1872-4973; 1878-0326; 1878-0326
• DOI: 10.1016/j.fsigen.2023.102946

The DNA Commission of the International Society for Forensic Genetics (ISFG) has developed a set of nomenclature recommendations for short tandem repeat (STR) sequences. These recommendations follow the 2016 considerations of the DNA Commission of the ISFG, incorporating the knowledge gained through research and population studies in the intervening years. While maintaining a focus on backward compatibility with the CE data that currently populate national DNA databases, this report also looks to the future with the establishment of recommended minimum sequence reporting ranges to facilitate interlaboratory comparisons, automated solutions for sequence-based allele designations, a suite of resources to support bioinformatic development, guidance for characterizing new STR loci, and considerations for incorporating STR sequences and other new markers into investigative databases.