Immune Response to COVID-19 Vaccination in Elite Athletes

This study analyses the immune response of elite athletes after COVID-19 vaccination with double-dose mRNA and a single-dose vector vaccine. Immunoglobulin G (IgG) antibody titers, neutralizing activity, CD4 and CD8 T-cells were examined in blood samples from 72 athletes before and after vaccination...

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Bibliographic Details
Published in:Exercise immunology review 2024, Vol.30, p.63
Main Authors: Halmans, Lea, Venhorst, Andreas, Klemis, Verena, Schmidt, Tina, Greiß, Franziska, Sester, Urban, Gärtner, Barabara C, Sester, Martina, Meyer, Tim
Format: Article
Language:English
Subjects:
2019-nCoV Vaccine mRNA-1273 - administration & dosage
2019-nCoV Vaccine mRNA-1273 - immunology
Adult
Antibodies, Neutralizing - blood
Antibodies, Viral - blood
Athletes
BNT162 Vaccine - administration & dosage
BNT162 Vaccine - immunology
CD4-Positive T-Lymphocytes - immunology
CD8-Positive T-Lymphocytes - immunology
COVID-19 - immunology
COVID-19 - prevention & control
COVID-19 Vaccines - administration & dosage
COVID-19 Vaccines - immunology
Female
Humans
Immunoglobulin G - blood
Male
SARS-CoV-2 - immunology
Spike Glycoprotein, Coronavirus - immunology
Vaccination
Young Adult
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Summary:This study analyses the immune response of elite athletes after COVID-19 vaccination with double-dose mRNA and a single-dose vector vaccine. Immunoglobulin G (IgG) antibody titers, neutralizing activity, CD4 and CD8 T-cells were examined in blood samples from 72 athletes before and after vaccination against COVID-19 (56 mRNA (BNT162b2 / mRNA-1273), 16 vector (Ad26.COV.2) vaccines). Side effects and training time loss was also recorded. Induction of IgG antibodies (mRNA : 5702 BAU/ml ; 4343 BAU/ml (hereafter: median), vector: 61 BAU/ml ; 52 BAU/ml, p
ISSN:1077-5552