Transcranial direct current stimulation improves seizures frequency in drug-resistant epilepsy: A systematic-review and meta-analysis of randomized controlled trials

•Active tDCS is associated with a significant decrease in seizure frequency among patients with DRE.•Active tDCS could serve as a valuable adjunctive therapy in the armamentarium for treating patients with refractory epilepsy who continue to experience a high frequency of seizures,•Active tDCS appar...

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Bibliographic Details
Published in:Epilepsy & behavior 2024-10, Vol.159, p.109974, Article 109974
Main Authors: Lima, A.E., Telles, J.P., Dantas, J., Fernandes, A.C., Ribeiro, G.B.S., Barbosa, V.L., Castro-Lima, H.
Format: Article
Language:English
Subjects:
Drug Resistant Epilepsy - therapy
Humans
Randomized Controlled Trials as Topic
Seizures - therapy
Transcranial Direct Current Stimulation - methods
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Summary:•Active tDCS is associated with a significant decrease in seizure frequency among patients with DRE.•Active tDCS could serve as a valuable adjunctive therapy in the armamentarium for treating patients with refractory epilepsy who continue to experience a high frequency of seizures,•Active tDCS apparent has low risk of adverse effects. This is particularly significant in this patient population, as the introduction of additional ASMs is often constrained by the adverse effects of medications.
ISSN:1525-5050
1525-5069
1525-5069
DOI:10.1016/j.yebeh.2024.109974