Ocular surface parameters repeatability and agreement —A comparison between Keratograph 5M and IDRA

• Published in: Contact lens & anterior eye 2024-12, Vol.47 (6), p.102281, Article 102281
• Main Authors: Yin Chan, Ka, Liao, Xulin, Guo, Biyue, Tse, Jimmy S.H., Li, Peter H., Cheong, Allen M.Y., Ngo, William, Lam, Thomas C.
• Format: Article
• Language: English
• Subjects: Adult; Cornea; Diagnostic Techniques, Ophthalmological - instrumentation; Dry eye; Dry Eye Syndromes - diagnosis; Female; Humans; IDRA; Keratograph 5M; Male; Middle Aged; NIBUT; Repeatability; Reproducibility of Results; Tear film stability; Tears - chemistry; Tears - physiology; Young Adult
• ISSN: 1367-0484; 1476-5411; 1476-5411
• DOI: 10.1016/j.clae.2024.102281

To evaluate the repeatability and agreement in dry eye measurements using Oculus Keratograph 5M (K5M) and SBM Sistemi IDRA (IDRA). A total of 108 participants were enrolled and 108 eyes were evaluated. Tear meniscus height (TMH) and first and average non-invasive break-up time (NIBUT) were measured using the K5M and IDRA (order randomly assigned). TMH was measured using the built-in caliper tool while NIBUT was computed by the automatic algorithm of the instruments. The Bland Altman plots analysis showed a good agreement between the two instruments for TMH (95 % Limits of Agreement (LoA), −0.17 to 0.16), but not the first NIBUT (95 % LoA, −8.13 to 14.79) and average NIBUT (95 % LoA, −7.89 to 10.32). The values of the first and average NIBUT measured using IDRA were significantly shorter than in K5M (difference = median (IQR) −2.75 (−6.48- −0.28)s, p