Unchanged incidence of major adverse events amidst rising surgical interventions for osteoporotic vertebral fractures, 2015–2021

Summary This study investigated treatment trends and major adverse events in patients hospitalized for osteoporotic vertebral fracture (OVF). The frequency of surgical interventions for OVF increased significantly, but this did not decrease major adverse events. The findings underscore the necessity...

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Bibliographic Details
Published in:Archives of osteoporosis 2024-08, Vol.19 (1), p.71, Article 71
Main Authors: Masuda, Soichiro, Fukasawa, Toshiki, Otsuki, Bungo, Murata, Koichi, Shimizu, Takayoshi, Sono, Takashi, Honda, Shintaro, Shima, Koichiro, Sakamoto, Masaki, Matsuda, Shuichi, Kawakami, Koji
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cross-Sectional Studies
Endocrinology
Female
Hospitalization - statistics & numerical data
Humans
Incidence
Japan - epidemiology
Male
Medicine
Medicine & Public Health
Original Article
Orthopedics
Osteoporotic Fractures - epidemiology
Osteoporotic Fractures - surgery
Postoperative Complications - epidemiology
Spinal Fractures - epidemiology
Spinal Fractures - surgery
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Summary:Summary This study investigated treatment trends and major adverse events in patients hospitalized for osteoporotic vertebral fracture (OVF). The frequency of surgical interventions for OVF increased significantly, but this did not decrease major adverse events. The findings underscore the necessity for reevaluating OVF management strategies. Purpose Osteoporotic vertebral fracture (OVF) is a common condition in the aging population, often leading to increased morbidity and mortality. Here, we analyzed treatment trends and incidence of major adverse events in patients hospitalized for OVF. Methods We conducted a cross-sectional descriptive study, using a large Japanese hospital administrative database. The cohort included hospitalized patients aged 65 years or older, admitted for OVF from January 2015 to December 2021. The primary outcomes were the trend in the proportion of the patients undergoing surgery for OVF and the incidence of major adverse events within 30 days of admission. As a secondary outcome, we evaluated the trend in hospitalization costs. Results The study cohort consisted of 14,714 patients, with a mean age of 82.4 years. There was a significant increase in surgical interventions for OVF, from 3.7% of patients in 2015 to 9.8% in 2021 ( p  
ISSN:1862-3514
1862-3514
DOI:10.1007/s11657-024-01428-w