One-year changes in body composition and musculoskeletal health following metabolic/bariatric surgery

There are limited comparative studies between one anastomosis gastric bypass (OAGB) versus Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on body composition and musculoskeletal health. To compare changes in body composition, areal bone mineral density (aBMD), muscle strength, and physi...

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Published in:The journal of clinical endocrinology and metabolism 2024-07
Main Authors: Jassil, Friedrich C, Papageorgiou, Maria, Mackay, Emily, Carnemolla, Alisia, Kingett, Helen, Doyle, Jacqueline, Kirk, Amy, Lewis, Neville, Montagut, Gemma, Marvasti, Parastou, Brown, Adrian, Chaiyasoot, Kusuma, Zakeri, Roxanna, Mok, Jessica, Wingrove, Jed, Collet, Tinh-Hai, Devalia, Kalpana, Parmar, Chetan, Makaronidis, Janine, Batterham, Rachel L
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Language:English
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Summary:There are limited comparative studies between one anastomosis gastric bypass (OAGB) versus Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on body composition and musculoskeletal health. To compare changes in body composition, areal bone mineral density (aBMD), muscle strength, and physical function in the first year following OAGB, RYGB and SG within a UK-based healthcare setting. This is a secondary analysis of the BARI-LIFESTYLE trial in 119 adults (77% women; mean±SD, age: 45.9±10.3 years; BMI: 43.6±5.5 kg/m2) who underwent OAGB (n=19), RYGB (n=39) and SG (n=61). Body composition and aBMD by dual energy x-ray absorptiometry, handgrip strength, sit-to-stand (STS) test and 6-minute walking test (6MWT) were assessed pre-surgery and at 12 months post-surgery. OAGB, RYGB, and SG exhibited similar reductions in body weight, body fat and lean mass (within-group comparisons, p
ISSN:0021-972X
1945-7197
1945-7197
DOI:10.1210/clinem/dgae496