Evaluation of a medical student-delivered smoking prevention program utilizing a face-aging mobile app for secondary schools in Germany: The Education Against Tobacco cluster-randomized controlled trial

• Published in: European journal of cancer (1990) 2024-09, Vol.209, p.114255, Article 114255
• Main Authors: Brinker, Titus J., Krieghoff-Henning, Eva I., Suhre, Janina L., Silchmüller, Marc Phillipp, Divizieva, Evgenia, Wilhelm, Jilada, Hillebrand, Gabriel, Haney, Ailís C., Srivastava, Aayushi, Haney, Caelán M., Seeger, Werner, Penka, Dominik, Gall, Henning, Gaim, Benedikt, Glisic, Lazar, Stark, Tobias, Swoboda, Susanne M., Baumermann, Sonja, Brieske, Christian M., Jakob, Lena, Fahrner, Hannah Maria, Anhuef, Ole, Schmidt, Selina Marisa, Alfitian, Jonas, Taha, Lava, Beißwenger, Hanna, Groneberg, David A., Thomas, Roger E., Fröhling, Stefan, von Kalle, Christof, Baudson, Tanja Gabriele, Buslaff, Fabian, Mons, Ute
• Format: Article
• Language: English
• Subjects: Prevention; Schools; Smoking; Smoking prevention; Tobacco prevention
• ISSN: 0959-8049; 1879-0852; 1879-0852
• DOI: 10.1016/j.ejca.2024.114255

To reduce smoking uptake in adolescents, the medical students' network Education Against Tobacco (EAT) has developed a school-based intervention involving a face-aging mobile app (Smokerface). A two-arm cluster-randomized controlled trial was conducted, evaluating the 2016 EAT intervention, which employed the mobile app Smokerface and which was delivered by medical students. Schools were randomized to intervention or control group. Surveys were conducted at baseline (pre-intervention) and at 9, 16, and 24 months post-intervention via paper & pencil questionnaires. The primary outcome was the difference in within-group changes in smoking prevalence between intervention and control group at 24 months. Overall, 144 German secondary schools comprising 11,286 pupils participated in the baseline survey, of which 100 schools participated in the baseline and at least one of the follow-up surveys, yielding 7437 pupils in the analysis sample. After 24 months, smoking prevalence was numerically lower in the intervention group compared to control group (12.9 % vs. 14.3 %); however, between-group differences in change in smoking prevalence between baseline and 24-months follow-up (OR=0.83, 95 %-CI: 0.64–1.09) were not statistically significant (p = 0.176). Intention to start smoking among baseline non-smokers declined non-significantly in the intervention group (p = 0.064), and remained essentially unchanged in the control group, but between-group differences in changes at the 24-months follow-up (OR=0.88, 0.64–1.21) were not statistically significant (p = 0.417). While a trend towards beneficial effects of the intervention regarding smoking prevalence as well as intention to start smoking among baseline non-smokers was observed, our smoking prevention trial demonstrated no significant effect of the intervention. •A face-aging app intervention aimed to reduce adolescent smoking uptake.•Two-arm cluster-randomized controlled trial with 144 German secondary schools.•No significant difference in smoking prevalence change at 24 months (p = 0.176).•Subgroup analyses showed a tendency towards benefits among boys and grammar school pupils.•Intention to start smoking declined non-significantly in the intervention group (p = 0.064).