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A case report of acute Q fever with low-read detection of Coxiella burnetii genome by next-generation metagenomic sequencing

The case presents a 47-year-old man with sudden abdominal pain and fever, but the cause was uncertain. Through metagenomic next-generation sequencing (mNGS) and detecting Q fever antibodies in serum, along with the patient's clinical and epidemiological history, a precise diagnosis was made, en...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2024-10, Vol.110 (2), p.116434, Article 116434
Main Authors: Wu, Xianglin, Xu, Aohong, Tian, Feng, Yang, Juhong, Lin, Liekun, Zhai, Mingzhu, Wu, Benqing, Zheng, Yi
Format: Article
Language:English
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Summary:The case presents a 47-year-old man with sudden abdominal pain and fever, but the cause was uncertain. Through metagenomic next-generation sequencing (mNGS) and detecting Q fever antibodies in serum, along with the patient's clinical and epidemiological history, a precise diagnosis was made, enabling timely and proper treatment.
ISSN:0732-8893
1879-0070
1879-0070
DOI:10.1016/j.diagmicrobio.2024.116434