Seroreversion in HIV-Associated Bilateral CMV Retinitis: A Challenging Case Report

To report a case of seroreversion in a patient with HIV-associated bilateral CMV retinitis and the challenges associated with detection of this phenomenon in late stages of HIV. Retrospective single case report. The clinical picture of the patient on presentation was suggestive of viral retinitis. P...

Full description

Saved in:
Bibliographic Details
Published in:Ocular immunology and inflammation 2024-08, p.1-5
Main Authors: Sriram, Radhika, Mahendradas, Padmamalini, Hande, Prathiba, Patil, Aditya, Kawali, Ankush, Mishra, Sai Bhakti, Rizvi, Sara, Shetty, Rohit
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To report a case of seroreversion in a patient with HIV-associated bilateral CMV retinitis and the challenges associated with detection of this phenomenon in late stages of HIV. Retrospective single case report. The clinical picture of the patient on presentation was suggestive of viral retinitis. PCR confirmed a diagnosis of CMV retinitis. Serology for HIV-1 & 2 was negative. A viral load of HIV and CD-4 count confirmed his sero status to be positive for HIV. Improvement in visual acuity and slow resolution of the lesion was noted with both anti-viral for CMV and HIV. A repeat HIV-1 testing was positive with an improvement in CD4 count. In highly suspicious individual, with a negative serology (post screening test) for HIV, the disease status should be confirmed by testing the individual for HIV viral load and CD4 count.
ISSN:0927-3948
1744-5078
1744-5078
DOI:10.1080/09273948.2024.2385606