Seroreversion in HIV-Associated Bilateral CMV Retinitis: A Challenging Case Report

To report a case of seroreversion in a patient with HIV-associated bilateral CMV retinitis and the challenges associated with detection of this phenomenon in late stages of HIV. Retrospective single case report. The clinical picture of the patient on presentation was suggestive of viral retinitis. P...

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Published in:Ocular immunology and inflammation 2024-08, p.1-5
Main Authors: Sriram, Radhika, Mahendradas, Padmamalini, Hande, Prathiba, Patil, Aditya, Kawali, Ankush, Mishra, Sai Bhakti, Rizvi, Sara, Shetty, Rohit
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container_title Ocular immunology and inflammation
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creator Sriram, Radhika
Mahendradas, Padmamalini
Hande, Prathiba
Patil, Aditya
Kawali, Ankush
Mishra, Sai Bhakti
Rizvi, Sara
Shetty, Rohit
description To report a case of seroreversion in a patient with HIV-associated bilateral CMV retinitis and the challenges associated with detection of this phenomenon in late stages of HIV. Retrospective single case report. The clinical picture of the patient on presentation was suggestive of viral retinitis. PCR confirmed a diagnosis of CMV retinitis. Serology for HIV-1 & 2 was negative. A viral load of HIV and CD-4 count confirmed his sero status to be positive for HIV. Improvement in visual acuity and slow resolution of the lesion was noted with both anti-viral for CMV and HIV. A repeat HIV-1 testing was positive with an improvement in CD4 count. In highly suspicious individual, with a negative serology (post screening test) for HIV, the disease status should be confirmed by testing the individual for HIV viral load and CD4 count.
doi_str_mv 10.1080/09273948.2024.2385606
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title Seroreversion in HIV-Associated Bilateral CMV Retinitis: A Challenging Case Report
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