Prognostic Impact of the Ratio of Hemoglobin to Red Blood Cell Distribution Width in Patients after Acute Decompensated Heart Failure

• Published in: Internal Medicine 2024, pp.3691-24
• Main Authors: Kanzaki, Yusuke, Minamisawa, Masatoshi, Motoki, Hirohiko, Suzuki, Sho, Okuma, Yukari, Kanai, Masafumi, Machida, Keisuke, Kimura, Kazuhiro, Ueki, Yasushi, Yoshie, Koji, Oguchi, Yasutaka, Kato, Tamon, Saigusa, Tatsuya, Ebisawa, Soichiro, Okada, Ayako, Kuwahara, Koichiro
• Format: Article
• Language: English
• Subjects: Heart failure; Prognosis; Red blood cell distribution width
• ISSN: 0918-2918; 1349-7235; 1349-7235
• DOI: 10.2169/internalmedicine.3691-24

Objective The ratio of hemoglobin to red blood cell distribution width (Hb/RDW) is a simple and readily available tool associated with adverse outcomes in chronic heart failure (HF). However, the association between the Hb/RDW ratio and mortality in patients with acute decompensated HF (ADHF) is unclear. The goal of this study was to investigate the relationship between the Hb/RDW ratio and mortality in patients after ADHF. Methods This single-center study included clinical and laboratory data collected at baseline, with patients prospectively followed-up for a median period of 3.1 years. The patients were divided into two groups based on their median Hb/RDW ratio. Patients We evaluated 250 consecutive patients hospitalized for ADHF at Shinshu University Hospital between July 2014 and March 2019. Results In our study cohort (median age, 76 [66-83] years; 62.8 % male), all-cause death was observed in 91 patients (incidence rate: 12.7 per 100 patient-years). A Kaplan-Meier analysis revealed that patients in the lower Hb/RDW ratio group (