Non-invasive estimation of cerebrospinal fluid pressure in idiopathic intracranial hypertension: magnetic resonance imaging analysis of optic nerve and eyeball

Invasive methods such as lumbar puncture and intraventricular catheters are commonly used to measure intracranial pressure (ICP). This study aims to develop quantitative and non-invasive techniques to measure ICP in patients with Idiopathic Intracranial Hypertension (IIH) using magnetic resonance im...

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Bibliographic Details
Published in:Acta neurologica Belgica 2024-08
Main Authors: Kula, Aslı Yaman, Polat, Yağmur Başak, Atasoy, Bahar, Yiğit, Mehmet, Kırık, Furkan, Pasin, Özge, Alkan, Alpay
Format: Article
Language:English
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Summary:Invasive methods such as lumbar puncture and intraventricular catheters are commonly used to measure intracranial pressure (ICP). This study aims to develop quantitative and non-invasive techniques to measure ICP in patients with Idiopathic Intracranial Hypertension (IIH) using magnetic resonance imaging (MRI) findings. MRI data obtained from 50 patients with IIH and 30 age- and sex- matched controls were analyzed and optic nerve sheath diameter (ONSD), eyeball transverse diameter (ETD) and optic nerve diameter (OND) were measured. ONSD, ONSD/ETD and OND/ONSD indexes were calculated according to different ONSD measurement distances. Correlations of MRI findings with ICP were calculated. Sensitivity and specificity of all methods were analyzed. ONSD and ONSD/ETD index at 3 mm and 10 mm behind the eyeball were significantly higher (p 
ISSN:2240-2993
2240-2993
DOI:10.1007/s13760-024-02620-y