Modulating alginate-polyurethane elastomer properties: Influence of NCO/OH ratio with aliphatic diisocyanate

• Published in: International journal of biological macromolecules 2024-10, Vol.278 (Pt 2), p.134657, Article 134657
• Main Authors: Usman, Ali, Hussain, Muhammad Tahir, Akram, Nadia, Zuber, Mohammad, Sultana, Sitwat, Aftab, Waseem, Zia, Khalid Mahmood, Maqbool, Muhammad, Alanazi, Yousef M., Nazir, Ahsan, Javaid, Muhammad Asif
• Format: Article
• Language: English
• Subjects: Alginates - chemistry; Biocompatible Materials - chemistry; Biomaterials; Elastomers; Elastomers - chemistry; Hydrophobic and Hydrophilic Interactions; Isocyanates - chemistry; Materials Testing; NCO/OH ratio; Polyurethanes; Polyurethanes - chemistry; Sodium alginate; Spectroscopy, Fourier Transform Infrared; Temperature; Tensile Strength
• ISSN: 0141-8130; 1879-0003; 1879-0003
• DOI: 10.1016/j.ijbiomac.2024.134657

This research addresses the need for enhanced biomaterials by investigating the influence of the NCO/OH ratio on sodium alginate-based polyurethane elastomers(Al-PUEs), offering novel insights into their structural, thermal, mechanical and swelling behavior. Al-PUEs were prepared by blending the chain extenders with key ingredients in a specific molar ratio using aliphatic HMDI and HTPB monomers. The chemical linkages, crystalline behavior, homogeneity, and surface morphology of PUEs were evaluated by FT-IR, XRD, SEM, and EDX analysis. Thermo-mechanical studies were performed using TGA, DSC and tensile testing. Swelling behavior and absorption analysis were analyzed in DMSO and water. The analysis indicated that the hydrophilicity and swelling behavior of the prepared PUEs were affected by the addition of sodium alginate content. The results exhibit the tailor-made network structure of Al-PUEs, resulting in better thermal stability, elasticity of materials via stress-strain behavior and marvelous characteristic features than traditional high-tech yields. Furthermore, the resulting Al-PUEs are potential candidates for biomedical implants. Graphical representation for the synthesis of alginate-based polyurethane elastomers. [Display omitted]