Incidence of complications and functional outcomes following segmental femoral shaft fractures: a critical review of the literature

• Published in: European journal of orthopaedic surgery & traumatology 2024-08, Vol.34 (6), p.2891-2902
• Main Authors: Vasilopoulou, Anastasia, Karampitianis, Spyridon, Chloros, George D., Giannoudis, Peter V.
• Format: Article
• Language: English
• Subjects: Adult; Bone Plates; Female; Femoral Fractures - surgery; Fracture Fixation, Intramedullary - adverse effects; Fracture Fixation, Intramedullary - methods; Fractures; Fractures, Open - complications; Fractures, Open - surgery; General Review; Humans; Incidence; Injuries; Male; Medicine; Medicine & Public Health; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Surgical Orthopedics; Traumatic Surgery; Treatment Outcome
• ISSN: 1432-1068; 1633-8065; 1432-1068
• DOI: 10.1007/s00590-024-04065-8

Background Although segmental femoral shaft fractures (SFSF) are very challenging to manage, there has been no critical evaluation of the current practices and outcomes. The aim of this study is to evaluate their characteristics, management trends, outcomes, and complications. Methods A literature search was conducted via the SCOPUS, Embase (via SCOPUS) and MEDLINE (via PubMed) between 1995 and 2023. Studies were included if they reported patient demographics, mechanism of injury, classification of fractures, associated injuries, type of management, outcomes, and complications. Exclusion criteria: only diaphyseal fractures were included and proximal and distal femoral fractures were excluded from this study. Results Overall, 22 studies met the inclusion criteria reporting on 313 patients. Mean age was 36.2 years with male–female ratio of 4.8 to 1. The majority were high-energy fractures secondary to road traffic accidents and 16% were open. The most commonly associated injuries included chest injury (27%) and lower leg fractures (24%). Treatment consisted of intramedullary nailing (IMN) (72%), plating (22%) or both combined (6%). Outcomes reported: good in 70%, fair in 10%, excellent in 19% and poor in 2% of cases. Mean time to union was 20 weeks. Complications are reported in 24% of cases, with most common delayed union (5%) and non-union (4%). Conclusion SFSF are high-energy fractures occurring most commonly in young males, are open in 16% of cases and have significant associated injuries. In their overwhelming majority, IMN is the mainstay of treatment. The expected outcome is generally good in 70% of cases, although not devoid of complications in 24% of cases and patients must be aware of this during the consent process.