COVID-19 throughout pandemic waves and virus variants: a real-life experience in an Italian hospital

New therapies and vaccines changed the management of COVID-19. The aim of this retrospective study was to describe characteristics, in-hospital mortality and its predictors in patients with moderate/severe COVID-19, considering the 4 different pandemic waves and viral variants' prevalence from...

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Bibliographic Details
Published in:Journal of chemotherapy (Florence) 2024-08, p.1
Main Authors: Dettori, Silvia, Brucci, Giorgia, Portunato, Federica, Ponzano, Marta, Magnasco, Laura, Mirabella, Michele, Magnè, Federica, Delfino, Emanuele, Balletto, Elisa, Sepulcri, Chiara, Vena, Antonio, Giacobbe, Daniele Roberto, Marelli, Cristina, Ball, Lorenzo, Mikulska, Malgorzata, Di Biagio, Antonio, Bruzzone, Bianca, Signori, Alessio, Mora, Sara, Giacomini, Mauro, Dentone, Chiara, Bassetti, Matteo
Format: Article
Language:English
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Summary:New therapies and vaccines changed the management of COVID-19. The aim of this retrospective study was to describe characteristics, in-hospital mortality and its predictors in patients with moderate/severe COVID-19, considering the 4 different pandemic waves and viral variants' prevalence from February 2020 to January 2022. Among 1135 patients included, 873 (77%) had at least one comorbidity, 177 (16%) were immunocompromised. From waves 1 to 4, patients with severe respiratory failure and ICU admission decreased over time (  
ISSN:1973-9478
1973-9478
DOI:10.1080/1120009X.2024.2384321