Preoperative Hypoalbuminemia is Associated With Higher 30-day Mortality and Complications After Esophagectomy

Background Serum albumin level is routinely screened during preoperative assessments as a biomarker for poor nutritional status and/or concurrent inflammation. In esophagectomy, while early postoperative hypoalbuminemia is associated with a higher risk of adverse surgical outcomes, the effects of pr...

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Bibliographic Details
Published in:The American surgeon 2025-01, Vol.91 (1), p.51-58
Main Authors: Li, Renxi, Zhu, Yueyao
Format: Article
Language:English
Subjects:
Age
Aged
Albumin
Biomarkers
Body mass index
Chronic obstructive pulmonary disease
Demographics
Esophageal cancer
Esophageal Neoplasms - mortality
Esophageal Neoplasms - surgery
Esophagectomy - adverse effects
Ethnicity
Female
Hemophilia
Humans
Hypoalbuminemia
Infections
Male
Malignancy
Matching
Middle Aged
Mortality
Mortality risk
Nutritional status
Postoperative Complications - epidemiology
Postoperative Complications - mortality
Postoperative period
Preoperative Period
Propensity Score
Proteins
Quality control
Retrospective Studies
Risk Factors
Sepsis
Serum albumin
Surgical anastomosis
Surgical outcomes
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Summary:Background Serum albumin level is routinely screened during preoperative assessments as a biomarker for poor nutritional status and/or concurrent inflammation. In esophagectomy, while early postoperative hypoalbuminemia is associated with a higher risk of adverse surgical outcomes, the effects of preoperative hypoalbuminemia on esophagectomy outcomes were conflicting. This study aimed to examine the effect of preoperative hypoalbuminemia on 30-day outcomes following esophagectomy. Methods National Surgical Quality Improvement Program (NSQIP) esophagectomy targeted database from 2016 to 2022 was used. Patients with preoperative serum albumin
ISSN:0003-1348
1555-9823
1555-9823
DOI:10.1177/00031348241278019