Alzheimer's and metabolism wed with IDO1

Kynurenine pathway inhibition reverses deficits in Alzheimer's mouse models.

Saved in:
Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2024-08, Vol.385 (6711), p.826-827
Main Authors: Johnson, Lance A, Macauley, Shannon L
Format: Article
Language:English
Subjects:
Alzheimer Disease - drug therapy
Alzheimer Disease - metabolism
Alzheimer's disease
Amyloid beta-Peptides - metabolism
Animal models
Animals
Availability
Brain
Disease Models, Animal
Etiology
Glucose
Glucose metabolism
Humans
Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism
Kynurenine - metabolism
Memory tasks
Metabolism
Mice
Neurodegenerative diseases
Neuronal-glial interactions
Spatial analysis
Spatial memory
Tau protein
Tryptophan - metabolism
β-Amyloid
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Kynurenine pathway inhibition reverses deficits in Alzheimer's mouse models.
ISSN:0036-8075
1095-9203
1095-9203
DOI:10.1126/science.adr5836