Prevalence of mental disorders among family members of individuals on the autism spectrum: systematic review and meta-analysis

Parenting a child on the autism spectrum presents particular challenges that can lead to increased stress, anxiety, and depression among family members. Therefore, we aimed to investigate the prevalence of mental disorders in first-degree relatives of individuals on the autism spectrum. This article...

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Bibliographic Details
Published in:European child & adolescent psychiatry 2024-09
Main Authors: Lins-Silva, Daniel H, Bandeira, Igor D, Faria-Guimarães, Daniela, Dorea-Bandeira, Ingrid, Tolentino, Arthur, Miranda-Scippa, Ângela, Hermens, Daniel F, Lucena, Rita
Format: Article
Language:English
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Summary:Parenting a child on the autism spectrum presents particular challenges that can lead to increased stress, anxiety, and depression among family members. Therefore, we aimed to investigate the prevalence of mental disorders in first-degree relatives of individuals on the autism spectrum. This article adheres to the Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols (PRISMA-P) guidelines, including studies indexed in PubMed/Medline, Embase, PsycINFO, Biblioteca Virtual em Saúde (BVS), and SciELO. Nineteen articles met eligibility criteria for the systematic review. Using a random-effects model (N = 93,876), we found a pooled prevalence of affective disorders of 13% in mothers of people on the autism spectrum (95% CI 7-21%; I  = 99%, p 
ISSN:1018-8827
1435-165X
1435-165X
DOI:10.1007/s00787-024-02575-8