Association between experienced stigma, anxiety, depression and loneliness among people with drug‐resistant tuberculosis in Lagos Nigeria: The moderating role of social support

• Published in: Tropical medicine & international health 2024-10, Vol.29 (10), p.882-894
• Main Authors: Adejumo, Olusola Adedeji, Haffejee, Firoza, Jinabhai, Champaklal, Daniel, Olusoji
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Anxiety; Anxiety - epidemiology; Anxiety - psychology; Cross-Sectional Studies; depression; Depression - epidemiology; Depression - psychology; drug resistant‐tuberculosis; experienced stigma; Female; Humans; Loneliness; Loneliness - psychology; Male; Mental depression; Middle Aged; Nigeria - epidemiology; Social interactions; Social Stigma; Social Support; Stigma; Tuberculosis; Tuberculosis, Multidrug-Resistant - drug therapy; Tuberculosis, Multidrug-Resistant - psychology; Young Adult
• ISSN: 1360-2276; 1365-3156; 1365-3156
• DOI: 10.1111/tmi.14046

Background This study assessed the moderating effect of social support on the association between experienced stigma versus anxiety, depression and loneliness among people with drug‐resistant tuberculosis. Methods A descriptive cross‐sectional study was conducted among 203 adults on treatment for drug‐resistant tuberculosis for at least 8 weeks. Validated scales were used to assess experienced stigma, anxiety, depression, loneliness and social support. Partial correlations and hierarchical multiple regression were used to determine the moderating effect of social support on the association between experienced stigma versus anxiety, depression and loneliness. The interaction was visualised using slope analysis. Results Anxiety, loneliness and depression were reported by 148 (72.9%), 114 (56.2%) and 128 (63.1%) of the 203 participants, respectively. Experienced stigma was positively associated with depression (B = 0.428, p