Prevalence and risk factors associated with coronary artery disease in Iranian patients with peripheral artery disease

• Published in: Journal of vascular nursing 2024-09, Vol.42 (3), p.154-158
• Main Authors: Rai, Alireza, Baridkazemi, Soheila, Sobhiyeh, Mohammadreza, Amiri, Masoumeh, Ghorbani, Mohammad, Shafiei, Sasan, Rahmanipour, Elham
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Angiography; CAD; Coronary Angiography; Coronary Artery Disease - complications; Coronary Artery Disease - epidemiology; Cross-Sectional Studies; Female; Humans; Hypertension; Iran; Iran - epidemiology; Male; Middle Aged; Peripheral Arterial Disease - complications; Peripheral Arterial Disease - epidemiology; Prevalence; PVD; Risk Factors
• ISSN: 1062-0303; 1532-6578; 1532-6578
• DOI: 10.1016/j.jvn.2024.04.001

It is well known that peripheral artery disease (PAD) and coronary artery disease (CAD) coexist and therefore, patients diagnosed with PAD have an increased chance of developing concomitant CAD. CAD-related complications could be a leading cause of postoperative mortality in individuals with PAD undergoing vascular surgery. We present a case series of 48 patients who underwent coronary angiography before vascular surgery and an updated review of previous reports to determine the prevalence of concomitant CAD in a convenience sample of Iranian patients. This cross-sectional study was performed on 48 patients with confirmed PAD admitted to Imam Ali Hospital, affiliated with the Kermanshah University of Medical Sciences (KUMS), Kermanshah Province, Iran. A vascular surgeon diagnosed PAD based on the patient's symptoms, Doppler ultrasound, and CT angiography (CTA). All patients underwent coronary angiography to determine if they also had CAD. We defined significant CAD as a ≥70% luminal diameter narrowing of a major epicardial artery or a ≥50% narrowing of the left main coronary artery. Of 48 patients, 35 (72.9%) were male, 13 (27.1%) were female, and the mean age was 64.18±12.11 years (range, 30 to 100 years). The incidence of CAD in patients with PVD was 85.42% (41/48). The patients with CAD were more likely to be hypertensive than those without CAD (80.5 vs. 14.3, p-value