Characteristics, Treatment, and Prognosis in Octogenarian and Older Patients With Acute Heart Failure in Japan　― Prospective Observational Study on Acute Pharmacotherapy and Prognosis in Management of Acute Heart Failure (POPEYE-AHF Registry)

• Published in: Circulation Journal 2024/09/06, pp.CJ-24-0299
• Main Authors: Kuwayama, Tasuku, Okumura, Takahiro, Kondo, Toru, Oishi, Hideo, Kimura, Yuki, Kazama, Shingo, Araki, Takashi, Hiraiwa, Hiroaki, Morimoto, Ryota, Kanashiro, Masaaki, Asano, Hiroshi, Kawaguchi, Katsuhiro, Yoshida, Yukihiko, Tanaka, Nobukiyo, Morishima, Itsuro, Murohara, Toyoaki
• Format: Article
• Language: English
• Subjects: Acute Disease; Acute heart failure; Age Factors; Aged; Aged, 80 and over; Aging population; Female; Heart Failure - drug therapy; Heart Failure - mortality; Hospitalization; Humans; Japan - epidemiology; Male; Multicenter prospective study; Patient Readmission - statistics & numerical data; Prognosis; Prospective Studies; Registries; Risk Factors; Stroke Volume; Treatment Outcome
• ISSN: 1346-9843; 1347-4820; 1347-4820
• DOI: 10.1253/circj.CJ-24-0299

Background: The number of older people in Japan is increasing more quickly than in other countries; with this aging of society, the number of elderly patients hospitalized for acute heart failure (HF) is also increasing. The treatment and prognosis of acute HF may be changing, but there are insufficient recent data, especially for octogenarian and older patients.Methods and Results: This study investigated the characteristics and treatment of acute HF patients in Japan. From 2018 to 2020, 1,146 patients from 7 Tokai area hospitals were followed for at least 1 year. The mean age was 78 years. Compared with patients aged