The mind and motion: exploring the interplay between physical activity and Mild Behavioral Impairment in dementia-free older adults

Physical inactivity in mid-life is a modifiable risk factor for dementia. Mild behavioral impairment (MBI) is a marker of potential neurodegenerative disease. We investigated the association between physical activity and MBI. Baseline data from the Canadian Platform for Research Online to Investigat...

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Bibliographic Details
Published in:International review of psychiatry (Abingdon, England) England), 2024-05, Vol.36 (3), p.196-207
Main Authors: Mudalige, Dinithi, Guan, Dylan X, Ballard, Clive, Creese, Byron, Corbett, Anne, Pickering, Ellie, Roach, Pamela, Smith, Eric E, Ismail, Zahinoor
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Behavior
Body mass index
Canada
Cholesterol
Cognition
Cognitive Dysfunction - physiopathology
Dementia
Dementia - physiopathology
Exercise
Exercise - physiology
Female
Humans
Hypertension
Male
Marital status
Middle Aged
Mind and body
Mobility
Older people
Physical activity
Quality of life
Severity
Strength training
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Summary:Physical inactivity in mid-life is a modifiable risk factor for dementia. Mild behavioral impairment (MBI) is a marker of potential neurodegenerative disease. We investigated the association between physical activity and MBI. Baseline data from the Canadian Platform for Research Online to Investigate Health, Quality of Life, Cognition, Behaviour, Function, and Caregiving in Aging (CAN-PROTECT) were used. Four categories of weekly physical activity (cardiovascular, mind-body, strength training, and physical labour) were derived from the Community Healthy Activities Model Program for Seniors questionnaire. MBI was measured using the MBI-Checklist. Multivariable negative binomial regressions modelled the association between the standardized physical activity duration and MBI severity, adjusted for age, sex, education, marital status, ethno cultural origin, occupation, hypertension, dyslipidemia, mobility, and body mass index. Every 1 SD increase in cardiovascular activity was associated with 8.42% lower MBI severity. In contrast, every 1 SD increase in physical labor duration was associated with 5.64% greater MBI severity. These associations were neither moderated by the frequency engaging in each physical activity nor by sex. Cardiovascular physical activity in older persons may reduce levels of non-cognitive dementia markers like MBI, comparable to effects seen in cognition, potentially modulating dementia risk.
ISSN:0954-0261
1369-1627
1369-1627
DOI:10.1080/09540261.2024.2360561