Parsing the thyroid cytopathology suspicious for malignancy diagnosis through molecular-derived risk of malignancy and other related parameters: Insights into nodule characteristics and practice patterns

Thyroid cytopathology cases with suspicious for malignancy (SFM) diagnosis often result in resection. However, molecular testing offers details that may provide additional insights. In this study, the molecular profiles of SFM cases from two institutions that routinely used ThyroSeq v3 (TSV3) were e...

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Bibliographic Details
Published in:Cancer cytopathology 2024-09
Main Authors: Starr, David, Tjendra, Youley, Velez Torres, Jaylou M, Gomez-Fernandez, Carmen, Khader, Samer N, Karslioglu-French, Esra, Yip, Linwah, Carty, Sally E, Skaugen, John M, Nikiforov, Yuri E, Seethala, Raja R, Ohori, N Paul
Format: Article
Language:English
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Summary:Thyroid cytopathology cases with suspicious for malignancy (SFM) diagnosis often result in resection. However, molecular testing offers details that may provide additional insights. In this study, the molecular profiles of SFM cases from two institutions that routinely used ThyroSeq v3 (TSV3) were examined. Following institutional review board approval, SFM thyroid cytopathology cases with TSV3 results were retrieved from the databases of two institutions. Molecular information including molecular-derived risk of malignancy (MDROM), cytologic-histologic correlation data, and other related parameters were calculated. Statistical comparisons were made with a p
ISSN:1934-662X
1934-6638
1934-6638
DOI:10.1002/cncy.22904