Desmoplastic melanoma

AbstractDesmoplastic melanoma is a rare fibrosing variant of melanoma. It typically affects elderly patients but can occasionally affect young or middle-aged individuals. Desmoplastic melanoma is relevant as a diagnostic pitfall for pure tumor variants’ distinct histopathologic and clinical features...

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Bibliographic Details
Published in:Clinics in dermatology 2024-09
Main Author: Busam, Klaus J., MD
Format: Article
Language:English
Subjects:
Dermatology
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Summary:AbstractDesmoplastic melanoma is a rare fibrosing variant of melanoma. It typically affects elderly patients but can occasionally affect young or middle-aged individuals. Desmoplastic melanoma is relevant as a diagnostic pitfall for pure tumor variants’ distinct histopathologic and clinical features. The latter includes a lower regional lymph node involvement frequency and a more favorable prognosis among thick melanomas. Classic cases of desmoplastic melanoma tend to carry a high mutation burden. Patients with metastases from those tumors tend to respond favorably to novel immunotherapies.
ISSN:0738-081X
1879-1131
1879-1131
DOI:10.1016/j.clindermatol.2024.09.005