Blood bank quality control: pH assessment methods in platelet concentrates

Platelet concentrates undergo progressive changes during storage, such as a decrease in pH. Additionally, pH and lactate production showed the strongest correlation with platelet survival in posttransfusion viability studies. pH measurement is a straightforward method for evaluating the quality cont...

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Bibliographic Details
Published in:Veterinary research communications 2024-12, Vol.48 (6), p.4129-4132
Main Authors: Lasta, Camila Serina, Hlavac, Nicole, Marcondes, Natália Aydos, de Almeida Lacerda, Luciana, de Faria Valle, Stella, González, Félix Hilário Díaz
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Blood
Blood banks
Blood Banks - standards
Blood platelets
Blood Platelets - chemistry
Blood Platelets - physiology
Blood Preservation - methods
Blood Preservation - standards
Blood Preservation - veterinary
Brief Report
Dogs - blood
Hydrogen-Ion Concentration
Life Sciences
Methods
pH effects
Platelets
Quality Control
Software
Veterinary Medicine/Veterinary Science
Zoology
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Summary:Platelet concentrates undergo progressive changes during storage, such as a decrease in pH. Additionally, pH and lactate production showed the strongest correlation with platelet survival in posttransfusion viability studies. pH measurement is a straightforward method for evaluating the quality control of blood components in blood bank practice. Our aim was to compare three pH assessment methods for canine platelet concentrates. The pH values of the canine platelet concentrates were assessed on the first day of storage using a calibrated pH meter, a portable gas analyzer and pH-indicator strips. The results from the pH meter and portable gas analyzer measurements were similar. The pH indicator strips presented higher average values compared to the other more reliable methods evaluated, which could result in the use of inadequate blood components. In conclusion, it is recommended to implement pH measurements using a pH meter for quality control in veterinary blood banks.
ISSN:0165-7380
1573-7446
1573-7446
DOI:10.1007/s11259-024-10536-4