Trajectories of perioperative nutritional status in patients with pancreatic tumor after surgery in six months

• Published in: European journal of oncology nursing : the official journal of European Oncology Nursing Society 2024-10, Vol.72, p.102687, Article 102687
• Main Authors: Yang, Hui-Ying, Shun, Shiow-Ching, Lee, Yun-Hsiang, Liou, Yan-Ting, Chou, Yun-Jen, Kuo, Hsuan-Ju, Tien, Yu-Wen, Lai, Sheng-Ru, Hung, Hung
• Format: Article
• Language: English
• Subjects: Adult; Aged; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Pancreatectomy; Pancreatectomy - adverse effects; Pancreatic Neoplasms - surgery; Pancreatic tumor; Perioperative Period; Postoperative Complications - epidemiology; Prospective Studies; Surgery; Symptom; Taiwan; Trajectories
• ISSN: 1462-3889; 1532-2122; 1532-2122
• DOI: 10.1016/j.ejon.2024.102687

To characterize subgroups with similar nutritional status trajectories during the 6-month period after pancreatectomy and to identify demographic and clinical characteristics influencing changes in nutritional status in each subgroup. This longitudinal prospective study recruited 112 patients with newly diagnosed pancreatic tumor from an outpatient pancreatic surgical department of a medical center in northern Taiwan between September 2016 and April 2019. Patients completed a demographic and clinical characteristics form, the Mini Nutritional Assessment scale, and the Symptom Severity Scale prior to surgery (T0), 3 months after surgery (T1), and 6 months after surgery (T2). Latent class growth analysis was used to investigate the trajectories of nutritional status. Generalized estimating equations were used to identify significant factors influencing each trajectory. Two latent groups of nutritional status trajectories were identified. Among 112 patients, 74.11% and 25.89% were classified as having high and low nutritional status trajectories, respectively. High nutritional status was significantly negatively correlated with changes in symptom severity. Low nutritional status was significantly negatively correlated with older age, surgical complications, and changes in symptom severity. Symptom severity has the most significant negative effect on perioperative nutritional status. Older age and surgical complications exert negative effects on perioperative nutritional status among patients with low nutritional status. These findings emphasize the need for nurses to identify at-risk individuals and provide individualized nutritional care to improve nutritional status in this population. This study was registered on ClinicalTrials.gov (trial registration number: NCT02900677; approved date: September 14th, 2016). Link: https://clinicaltrials.gov/ct2/show/NCT02900677. •Preoperative malnutrition affects the nutritional status after pancreatectomy.•Symptom severity is associated with malnutrition following pancreatectomy.•Patients with malnutrition tend to be older and have surgical complications.•Perioperative nutritional assessment can assist to identify at-risk individuals.