Why geneticists should care about male infertility

The widespread use of medically assisted reproduction fosters the false impression that the underlying causes of male infertility are not important to know. However, to improve men’s reproductive and long-term health, as well as the health of their offspring, large-scale genetic studies are essentia...

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Bibliographic Details
Published in:Nature reviews. Genetics 2024-12, Vol.25 (12), p.823-824
Main Authors: Veltman, Joris A., Tüttelmann, Frank
Format: Article
Language:English
Subjects:
631/208/2489/1512
692/699/2743
Agriculture
Animal Genetics and Genomics
Biomedical and Life Sciences
Biomedicine
Cancer Research
Collaboration
Comment
Disease
Fertility
Gene Function
Genes
Genetic testing
Genetics
Genomes
Genomics
Health risk assessment
Health risks
Human Genetics
Infertility
Mutation
Reproductive health
Sperm
Spermatogenesis
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Summary:The widespread use of medically assisted reproduction fosters the false impression that the underlying causes of male infertility are not important to know. However, to improve men’s reproductive and long-term health, as well as the health of their offspring, large-scale genetic studies are essential. Thus, reproductive genomics should be implemented in diagnostics as soon as possible. In this Comment, Veltman and Tüttelmann call on geneticists to further study male infertility and help to develop diagnostic strategies using state-of-the-art genomic approaches.
ISSN:1471-0056
1471-0064
1471-0064
DOI:10.1038/s41576-024-00773-3