Association Between Cardiorespiratory Fitness and Trend of Age-Related Rise in Arterial Stiffness in Individuals With and Without Hypertension or Diabetes

This study aimed to investigate whether higher cardiorespiratory fitness (CRF) can modify the trend of age-related rise in arterial stiffness in individuals with and without hypertension (HTN) or diabetes. The study included 4,935 participants who underwent maximal cardiopulmonary exercise testing w...

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Published in:American journal of hypertension 2024-12, Vol.38 (1), p.46-54
Main Authors: Jae, Sae Young, Lee, Kyung Hyun, Kim, Hyun Jeong, Kunutsor, Setor K, Pierce, Gary L, Hui, Stanley Sai-Chuen, Kang, Mira
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aging - physiology
Ankle Brachial Index
Cardiorespiratory Fitness
Cross-Sectional Studies
Diabetes Mellitus - epidemiology
Diabetes Mellitus - physiopathology
Exercise Test
Female
Humans
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - physiopathology
Male
Middle Aged
Pulse Wave Analysis
Risk Factors
Vascular Stiffness
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container_end_page 54
container_issue 1
container_start_page 46
container_title American journal of hypertension
container_volume 38
creator Jae, Sae Young
Lee, Kyung Hyun
Kim, Hyun Jeong
Kunutsor, Setor K
Pierce, Gary L
Hui, Stanley Sai-Chuen
Kang, Mira
description This study aimed to investigate whether higher cardiorespiratory fitness (CRF) can modify the trend of age-related rise in arterial stiffness in individuals with and without hypertension (HTN) or diabetes. The study included 4,935 participants who underwent maximal cardiopulmonary exercise testing with respiratory gas analysis in a health screening program. CRF was directly measured using peak oxygen uptake during the cardiopulmonary exercise test, while arterial stiffness was evaluated using brachial-ankle pulse wave velocity (baPWV). Participants with high CRF levels had significantly lower baPWV compared with those with low CRF levels, regardless of HTN or diabetes status (P 
doi_str_mv 10.1093/ajh/hpae124
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identifier ISSN: 0895-7061
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1941-7225
language eng
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source Oxford Journals Online
subjects Adult
Age Factors
Aged
Aging - physiology
Ankle Brachial Index
Cardiorespiratory Fitness
Cross-Sectional Studies
Diabetes Mellitus - epidemiology
Diabetes Mellitus - physiopathology
Exercise Test
Female
Humans
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - physiopathology
Male
Middle Aged
Pulse Wave Analysis
Risk Factors
Vascular Stiffness
title Association Between Cardiorespiratory Fitness and Trend of Age-Related Rise in Arterial Stiffness in Individuals With and Without Hypertension or Diabetes
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