Fungicide-albumin interactions: unraveling the complex relationship—a comprehensive review

This review will give an insight into the interactions of serum albumins, which are proteins found in the blood, with fungicides. There are molecular interactions between several fungicides and two serum albumin proteins: human serum albumin (HSA) and bovine serum albumin (BSA). The main objective o...

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Bibliographic Details
Published in:Biophysical reviews 2024-08, Vol.16 (4), p.417-439
Main Authors: Malik, Nisar Ahmad, Nazir, Nighat, Manzoor, Mehak, Gull, Faizan
Format: Article
Language:English
Subjects:
Biochemistry
Biological and Medical Physics
Biological Techniques
Biomedical and Life Sciences
Biophysics
Bovine serum albumin
Cell Biology
Fungicides
Human serum albumin
Life Sciences
Membrane Biology
Molecular interactions
Nanotechnology
Proteins
Review
Reviews
Serum albumin
Toxicity
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Summary:This review will give an insight into the interactions of serum albumins, which are proteins found in the blood, with fungicides. There are molecular interactions between several fungicides and two serum albumin proteins: human serum albumin (HSA) and bovine serum albumin (BSA). The main objective of this review is to through some light on the interactions of the fungicides with serum albumins and to highlight their toxicity level. The interactions of serum albumins with fungicides are complex and can be affected by the properties of the proteins themselves. This review provides valuable insight into the interactions between serum albumins and fungicides, which can help to know the efficacy and mechanism of fungicides and may help in designing new fungicides with low or no toxicity.
ISSN:1867-2450
1867-2469
DOI:10.1007/s12551-024-01190-w