Modern surgical strategies in pediatric neuroblastoma: Evolving approaches and treatment principles

Neuroblastoma, the most common extracranial solid tumor in children under the age of 5, has been described as early as the 19th century, and its complexity has continued to intrigue researchers, as well as medical and surgical specialists. At one end of the phenotypic spectrum, neuroblastoma is self...

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Bibliographic Details
Published in:Pediatric blood & cancer 2024-09, p.e31317
Main Authors: Williams, Keyonna M, Shah, Nikhil R, Chukkapalli, Sahiti, King, Sarah, Grant, Christa N, Brown, Erin G, Avanzini, Stefano, Lal, Dave R, Sarnacki, Sabine, Newman, Erika A
Format: Article
Language:English
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Summary:Neuroblastoma, the most common extracranial solid tumor in children under the age of 5, has been described as early as the 19th century, and its complexity has continued to intrigue researchers, as well as medical and surgical specialists. At one end of the phenotypic spectrum, neuroblastoma is self-limiting with minimal to no intervention required, while on the opposite end exists the challenge of refractory disease despite aggressive management and toxic systemic treatments. The goal of this review is to describe a comprehensive surgical perspective and contemporary approach to neuroblastoma.
ISSN:1545-5009
1545-5017
1545-5017
DOI:10.1002/pbc.31317