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Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis

In this review the most important techniques, which are developed to hyphenate capillary electrophoresis to mass spectrometry (CE-MS), suitable for forensic analysis, are summarized. Analytes of interest are divided into four main parts, namely, compounds with amine containing side chains, compounds...

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Bibliographic Details
Published in:The open chemical engineering journal 2007-11, Vol.1 (1), p.30-43
Main Authors: Huck, Christian W., Huck-Pezzei, Verena, Bakry, Rania, Bachmann, Stefan, Najam-ul-Haq, Muhammad, Rainer, Matthias, Bonn, Günther K.
Format: Article
Language:English
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Summary:In this review the most important techniques, which are developed to hyphenate capillary electrophoresis to mass spectrometry (CE-MS), suitable for forensic analysis, are summarized. Analytes of interest are divided into four main parts, namely, compounds with amine containing side chains, compounds with N-containing saturated ring structures, other heterocycles and peptides. Sample pre-treatments and direct injection modes used in CE-MS for forensic analysis are briefly discussed from critical point of view. Special emphasis is placed to point out the advantages of mass spectrometric detection compared to UV- and laser- induced fluorescence (LIF) detections.
ISSN:1874-1231
1874-1231
DOI:10.2174/1874123100701010030