Renal Cell Carcinoma With Tumor Thrombus Extending Into the Inferior Vena Cava and the Right Atrium Demonstrated by 68 Ga-DOTATATE PET/CT

Approximately 10% of all renal cell carcinoma (RCC) patients develop a venous tumor thrombus, a major negative prognostic factor. Surgical excision is commonly required for RCC patients with tumor thrombus. Accurate preoperative diagnosis and assessment of tumor thrombus level is vital because the l...

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Bibliographic Details
Published in:Clinical nuclear medicine 2024-11, Vol.49 (11), p.e630
Main Authors: Filizoglu, Nuh, Ozguven, Salih
Format: Article
Language:English
Subjects:
Carcinoma, Renal Cell - diagnostic imaging
Carcinoma, Renal Cell - pathology
Heart Atria - diagnostic imaging
Heart Atria - pathology
Humans
Kidney Neoplasms - diagnostic imaging
Kidney Neoplasms - pathology
Male
Middle Aged
Organometallic Compounds
Positron Emission Tomography Computed Tomography
Thrombosis - diagnostic imaging
Tomography, X-Ray Computed
Vena Cava, Inferior - diagnostic imaging
Vena Cava, Inferior - pathology
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Summary:Approximately 10% of all renal cell carcinoma (RCC) patients develop a venous tumor thrombus, a major negative prognostic factor. Surgical excision is commonly required for RCC patients with tumor thrombus. Accurate preoperative diagnosis and assessment of tumor thrombus level is vital because the level of thrombus may influence treatment decisions. MRI, contrast-enhanced CT, 18 F-FDG PET/CT, and 68 Ga-PSMA PET/CT have been used to diagnose and evaluate the extent of tumor thrombus in RCC. However, no case of RCC with inferior vena cava tumor thrombus showing 68 Ga-DOTATATE uptake has been reported yet. Herein, we report a case of metastatic RCC with tumor thrombus in the inferior vena cava on 68 Ga-DOTATATE PET/CT.
ISSN:1536-0229
1536-0229
DOI:10.1097/RLU.0000000000005487