Myofibroma with Atypical Features can Mimic Low-Grade Myofibroblastic Sarcoma: Two Paediatric Cases

Myofibroma is a rare benign mesenchymal tumor that frequently affects the pediatric population with a predilection for the head and neck region. About 10% of myofibroma cases, presenting atypical features, can be misinterpreted as low-grade myofibroblastic sarcoma (LGMS), with therapeutic and progno...

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Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2024-10, Vol.76 (5), p.4753-4756
Main Authors: Reyes, Magdalena Raquel Torres, Martins, Karina Helen, Posantes, Gabriela Esperanza Maradiaga, Zelaya, Florence Juana Maria Cuadra, Renderos, Sandra Guadalupe Góngora, León, Jorge Esquiche
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Language:English
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Clinical Report
Head and Neck Surgery
Medicine
Medicine & Public Health
Otorhinolaryngology
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container_title Indian journal of otolaryngology, and head, and neck surgery
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creator Reyes, Magdalena Raquel Torres
Martins, Karina Helen
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León, Jorge Esquiche
description Myofibroma is a rare benign mesenchymal tumor that frequently affects the pediatric population with a predilection for the head and neck region. About 10% of myofibroma cases, presenting atypical features, can be misinterpreted as low-grade myofibroblastic sarcoma (LGMS), with therapeutic and prognostic impact. Here, we report two pediatric cases of benign myofibroblastic tumors, one of them showing typical characteristics of myofibroma, the other was an atypical myofibroma, which initially mimicked low-grade myofibroblastic sarcoma. Atypical myofibromas, despite its distinctive characteristics, follow a benign course, similar with typical myofibroma. It is necessary to distinguish atypical myofibroma from low-grade myofibroblastic sarcoma and avoid unnecessary invasive therapy.
doi_str_mv 10.1007/s12070-024-04828-z
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subjects Clinical Report
Head and Neck Surgery
Medicine
Medicine & Public Health
Otorhinolaryngology
title Myofibroma with Atypical Features can Mimic Low-Grade Myofibroblastic Sarcoma: Two Paediatric Cases
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