Head-to-head comparison of DaVinci and Hugo™ RAS robotic platforms for robot-assisted radical prostatectomy: a systematic review and meta-analysis of comparative studies

• Published in: Prostate cancer and prostatic diseases 2024-10
• Main Authors: Ditonno, Francesco, Pettenuzzo, Greta, Montanaro, Francesca, De Bon, Lorenzo, Costantino, Sonia, Toska, Endri, Malandra, Sarah, Cianflone, Francesco, Bianchi, Alberto, Porcaro, Antonio Benito, Cerruto, Maria Angela, Veccia, Alessandro, Bertolo, Riccardo, Antonelli, Alessandro
• Format: Article
• Language: English
• ISSN: 1365-7852; 1476-5608; 1476-5608
• DOI: 10.1038/s41391-024-00908-x

We conducted a systematic review and meta-analysis of comparative studies to analyze intra- and postoperative outcomes of robot-assisted radical prostatectomy (RARP) using either DaVinci (DV-RARP) or Hugo™RAS (H-RARP) platforms. The study was registered in PROSPERO (CRD42024562326) and followed PRISMA guidelines. Literature search was conducted in June 2024 using academic databases, focusing on articles from 2021 to 2024. Research question focused on men with PCa (P) undergoing H-RARP (I) versus DV-RARP (C) to evaluate surgical, pathology, and functional outcomes (O), across comparative studies. Continuous variables were summarized using mean difference (MD) and categorical variables using odds ratio with 95% confidence intervals (CI). Heterogeneity was assessed using Cochran's Q test and I statistics. Publication bias was evaluated with Egger's and Begg's tests. Statistical analysis was performed with Stata®17.0, with significance set at p