Moving metabolomics into the routine of clinical laboratories: A forward-thinking strategy

•The next frontier of the clinical laboratory is the system biology approach.•Metabolomics represents the result of the interplay between the host and exposome.•ISO 23118:2021 contains specifications for standardizing the preanalytical phase.•A standard reference material is available to improve har...

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Bibliographic Details
Published in:Clinica chimica acta 2025-01, Vol.565, p.120012, Article 120012
Main Author: Mussap, Michele
Format: Article
Language:English
Subjects:
High throughput technologies
Individualized medicine
Laboratory medicine
Metabolomics
Molecular phenotype
System biology
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Summary:•The next frontier of the clinical laboratory is the system biology approach.•Metabolomics represents the result of the interplay between the host and exposome.•ISO 23118:2021 contains specifications for standardizing the preanalytical phase.•A standard reference material is available to improve harmonization in metabolomics.
ISSN:0009-8981
1873-3492
1873-3492
DOI:10.1016/j.cca.2024.120012