Lentigo Maligna Part I: Epidemiology, Risk Factors, and Diagnosis

Lentigo maligna (LM) is an increasingly common subtype of melanoma, presenting as a slow-growing tan-brown macule or patch with irregular borders arising on chronically solar-damaged skin. This two-part continuing medical education (CME) series provides an overview of LM. Part I reviews LM's ep...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2024-10
Main Authors: Gupta, Sameer, Shaughnessy, Michael, Rashid, Sarem, Stagner, Anna M., Fewkes, Jessica, Marghoob, Ashfaq A., Tsao, Hensin
Format: Article
Language:English
Subjects:
dermatopathology
dermoscopy
epidemiology
imaging
lentigo maligna
melanoma
Online Access:Get full text
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Summary:Lentigo maligna (LM) is an increasingly common subtype of melanoma, presenting as a slow-growing tan-brown macule or patch with irregular borders arising on chronically solar-damaged skin. This two-part continuing medical education (CME) series provides an overview of LM. Part I reviews LM's epidemiology, risk factors, and clinical presentation. Clinical tools to aid in diagnosis – such as dermoscopy and reflectance confocal microscopy – are discussed, as well as optimal biopsy strategies. Histopathology and current understanding of molecular underpinnings are also reviewed. Management of LM presents unique challenges given a predilection for subclinical spread on functionally and cosmetically sensitive areas such as the face. Part II reviews the two pillars of management including both surgical and non-surgical treatment options and surveillance.
ISSN:0190-9622
1097-6787
1097-6787
DOI:10.1016/j.jaad.2024.09.065