Patient characteristics and mortality across diagnostic settings in COPD

Many patients with chronic obstructive pulmonary disease (COPD) are diagnosed late, e.g., at first acute exacerbation of COPD (AECOPD). AECOPD increases the risk of death. We aim to investigate patient characteristics and mortality across diagnostic settings among patients with COPD. This nationwide...

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Bibliographic Details
Published in:Respiratory medicine 2024-11, Vol.234, p.107843, Article 107843
Main Authors: Buchardt, Sebastian Tristan Ehlert, Weinreich, Ulla Møller, Lindgren, Filip Lyng, Lauridsen, Marie Dam, Karlsen, Johanne Hermann, Kragholm, Kristian, Torp-Pedersen, Christian, Jacobsen, Peter Ascanius
Format: Article
Language:English
Subjects:
Acute exacerbation of chronic obstructive pulmonary disease
AECOPD
Age Factors
Aged
Aged, 80 and over
Chronic obstructive pulmonary disease
COPD
Denmark - epidemiology
Diagnostic setting
Disease Progression
Female
Hospitalization - statistics & numerical data
Humans
Male
Middle Aged
Primary Health Care - statistics & numerical data
Pulmonary Disease, Chronic Obstructive - diagnosis
Pulmonary Disease, Chronic Obstructive - mortality
Sex Factors
Citations: Items that this one cites
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Summary:Many patients with chronic obstructive pulmonary disease (COPD) are diagnosed late, e.g., at first acute exacerbation of COPD (AECOPD). AECOPD increases the risk of death. We aim to investigate patient characteristics and mortality across diagnostic settings among patients with COPD. This nationwide Danish study allocated 107,023 patients with a first-time registered COPD-related hospital contact between 2010 and 2018 based on diagnostic setting: primary care (prior inhalation medication use), hospital outpatient clinic or hospital admission. Multivariable logistic regression was employed to investigate patient characteristics and mortality across these diagnostic settings. In total, 81,035 (75.7 %) patients were diagnosed in primary care, median age 63 years (interquartile range (IQR) 53–71); 11,302 (10.6 %) at an outpatient clinic, median age 68 years (IQR 60–76), and 14,686 (13.7 %) during hospital admission, median age 73 years (IQR 65–81). Patient characteristics associated with diagnosis during hospital admission encompassed age (odds ratio (OR) 1.05, 95 % confidence interval (CI) 1.05–1.05, p 
ISSN:0954-6111
1532-3064
1532-3064
DOI:10.1016/j.rmed.2024.107843