FDG PET/CT in large vessel vasculitis

Large vessel vasculitides (LVV) such as giant cell arteritis, Takayasu arteritis and aortitis/periaortitis are characterised by immune-mediated inflammation of medium to large arteries. Clinical disease manifestations can be non-specific and diagnostic imaging plays an important role in the diagnost...

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Bibliographic Details
Published in:Journal of medical imaging and radiation oncology 2024-12, Vol.68 (8), p.881-892
Main Authors: Singh, Karan Bir, Nguyen, Katherine, Sammel, Anthony, Wegner, Eva A, Ho Shon, Ivan
Format: Article
Language:English
Subjects:
Computed tomography
Fluorodeoxyglucose F18
Giant Cell Arteritis - diagnostic imaging
Humans
Image acquisition
Positron emission
Positron Emission Tomography Computed Tomography - methods
Radiopharmaceuticals
Takayasu Arteritis - diagnostic imaging
Vasculitis - diagnostic imaging
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Summary:Large vessel vasculitides (LVV) such as giant cell arteritis, Takayasu arteritis and aortitis/periaortitis are characterised by immune-mediated inflammation of medium to large arteries. Clinical disease manifestations can be non-specific and diagnostic imaging plays an important role in the diagnostic pathway. In recent years, FDG PET/CT has proven to be a powerful metabolic tool that can provide a wholed body, non-invasive assessment of vascular inflammation. This review outlines the clinical features of large vessel vasculitis and the closely related entity of polymyalgia rheumatica, summarises the evidence for FDG PET/CT in the assessment of these conditions, and provides guidance for patient preparation, image acquisition and interpretation.
ISSN:1754-9477
1754-9485
1754-9485
DOI:10.1111/1754-9485.13800