Gestational diabetes mellitus – Can we do better with postpartum diabetes screening?

•Normal fasting plasma glucose levels 24-48 hours postpartum in women with gestational diabetes mellitus show a remarkable negative predictive value (99.30%) for type 2 diabetes at 6–12 weeks postpartum, particularly in low-risk cases managed by lifestyle changes.•With low compliance rates for stand...

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Bibliographic Details
Published in:European journal of obstetrics & gynecology and reproductive biology 2024-12, Vol.303, p.153-158
Main Authors: Zafrir-Danieli, Hadas, Houri, Ohad, Rotem, Reut, Weinberg-Almog, Dror, Bercovich, Or, Hadar, Eran, Berezowsky, Alexandra
Format: Article
Language:English
Subjects:
24 h fasting glucose
Adult
Alternative
Blood Glucose - analysis
Compliance
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - diagnosis
Diabetes, Gestational - blood
Diabetes, Gestational - diagnosis
Fasting - blood
Female
GDM
Gestational diabetes
Glucose Tolerance Test
Humans
Mass Screening - methods
Postpartum GTT
Postpartum Period - blood
Postpartum screening
Predictive Value of Tests
Pregnancy
Retrospective Studies
Citations: Items that this one cites
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Summary:•Normal fasting plasma glucose levels 24-48 hours postpartum in women with gestational diabetes mellitus show a remarkable negative predictive value (99.30%) for type 2 diabetes at 6–12 weeks postpartum, particularly in low-risk cases managed by lifestyle changes.•With low compliance rates for standard postpartum oral glucose tolerance tests, measuring FPG shortly after delivery emerges as a practical and effective screening tool to identify women at risk for future glucose intolerance and type 2 diabetes.•Immediate postpartum testing can effectively exclude diabetes risk in the majority of low-risk GDM cases, thereby aiding in targeted follow-up and management strategies. This study aimed to assess the accuracy of measuring fasting plasma glucose (FPG) within 24–48 h postpartum in women with gestational diabetes mellitus (GDM) as a predictor for abnormal 6–12-week postpartum oral glucose tolerance test (OGTT). A retrospective cohort study (2012–2021) included women with GDM and singleton pregnancies who had FPG levels recorded 24–28 h postpartum and underwent a 6–12-week OGTT. The study compared the predictive accuracy of these FPG readings with the OGTT results. Among 3128 GDM patients, 1163 (37.2 %) had a postpartum OGTT, with 935 (80.2 %) showing normal FPG (
ISSN:0301-2115
1872-7654
1872-7654
DOI:10.1016/j.ejogrb.2024.10.006