Stable and Minimum Size Solubilization of Membrane Proteins with Cocktails of Phospholipid Analogues

Membrane proteins (MPs) play important roles in various cellular processes and are major targets for drugs. Solubilization of MPs is often needed for structural and biophysical studies. For high-resolution nuclear magnetic resonance measurements, there is a size limit of the sample (

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Bibliographic Details
Published in:ACS applied materials & interfaces 2024-11, Vol.16 (46), p.63358-63367
Main Authors: Takagi, Mai, Nagatani, Ayana, Kawano, Kenichi, Hata, Ayami, Yokoyama, Azusa, Hayashida, Koichi, Hoshi, Haruka, Sakurai, Mao, Oyama, Tsuyoshi, Kuroda, Yusuke, Yamaoka, Yousuke, Fujiwara, Takahiro, Miyanoiri, Yohei, Hoshino, Masaru, Yano, Yoshiaki, Takasu, Kiyosei, Matsuzaki, Katsumi
Format: Article
Language:English
Subjects:
Biological and Medical Applications of Materials and Interfaces
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Description
Summary:Membrane proteins (MPs) play important roles in various cellular processes and are major targets for drugs. Solubilization of MPs is often needed for structural and biophysical studies. For high-resolution nuclear magnetic resonance measurements, there is a size limit of the sample (
ISSN:1944-8244
1944-8252
1944-8252
DOI:10.1021/acsami.4c15697