Eosinophils are sparse in homeostatic rectal tissue which impedes studying resident eosinophils

•Little is known on the amount of resident eosinophils in homeostatic tissues.•Using minimally invasive biopsy, only scarse eosinophils were found in the rectal tissue of completely healthy individuals.•This has major implications for studying resident eosinophils in healthy individuals.

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Bibliographic Details
Published in:Immunology letters 2024-12, Vol.270, p.106939, Article 106939
Main Authors: Pelgrim, Thomas C., Jukema, Bernard N., Vrisekoop, Nienke, Koenderman, Leo
Format: Article
Language:English
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Description
Summary:•Little is known on the amount of resident eosinophils in homeostatic tissues.•Using minimally invasive biopsy, only scarse eosinophils were found in the rectal tissue of completely healthy individuals.•This has major implications for studying resident eosinophils in healthy individuals.
ISSN:0165-2478
1879-0542
1879-0542
DOI:10.1016/j.imlet.2024.106939