Visible Light-Induced Three-Component Alkoxyalkylation of Alkenes with α‑Halocarbonyls and Alcohols

A visible-light-induced three-component alkoxyalkylation of alkenes has been developed under the photocatalysis of fac-Ir­(ppy)3. The alkene substrate scope included aryl and aliphatic alkenes as well as electron-rich and electron-deficient alkenes, allowing the facile coupling with a diverse array...

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Published in:Journal of organic chemistry 2024-12, Vol.89 (23), p.17621-17634
Main Authors: Chowdhury, Soumyadeep Roy, Kim, Hun Young, Oh, Kyungsoo
Format: Article
Language:English
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alkenes
organic chemistry
photocatalysis
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creator Chowdhury, Soumyadeep Roy
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description A visible-light-induced three-component alkoxyalkylation of alkenes has been developed under the photocatalysis of fac-Ir­(ppy)3. The alkene substrate scope included aryl and aliphatic alkenes as well as electron-rich and electron-deficient alkenes, allowing the facile coupling with a diverse array of α-halocarbonyl compounds. The redox potential-guided orchestration of radical processes with precision allows rapid access to highly functionalized products that are useful building blocks in organic synthesis.
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects alkenes
organic chemistry
photocatalysis
title Visible Light-Induced Three-Component Alkoxyalkylation of Alkenes with α‑Halocarbonyls and Alcohols
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