Impact of Meal Frequency on Insulin Resistance in Middle-Aged and Older Adults: A Prospective Cohort Study

Insulin resistance (IR) is central to metabolic disorders and significantly influenced by diet. Studies on meal frequency (MF) and metabolic indicators have shown mixed results. This study explores the link between MF and IR in middle-aged and older adults. This prospective cohort study included 4,5...

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Bibliographic Details
Published in:Diabetes & metabolism journal 2024-11
Main Authors: Ryu, Ha-Eun, Lee, Jong Hee, Park, Byoungjin, Heo, Seok-Jae, Kwon, Yu-Jin
Format: Article
Language:English
Online Access:Get full text
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Summary:Insulin resistance (IR) is central to metabolic disorders and significantly influenced by diet. Studies on meal frequency (MF) and metabolic indicators have shown mixed results. This study explores the link between MF and IR in middle-aged and older adults. This prospective cohort study included 4,570 adults aged 40 to 69 years from the Korean Genome and Epidemiologic Study. MF were divided into two groups based on whether they consumed three or more, or fewer than three, meals daily. IR was evaluated using the homeostasis model assessment of insulin resistance (HOMA-IR); participants were classified as IR if their HOMA-IR value was ??.5. Multiple Cox proportional hazard regression analyses were conducted to examine the association between MF and the incidence of IR. After adjusting for all variables, individuals in the MF ?? group showed a reduced incidence of IR compared to those in the MF
ISSN:2233-6079
2233-6087
2233-6087
DOI:10.4093/dmj.2024.0407