Study on the Impact of Hormone Therapy for Prostate Cancer on the Quality of Life and the Psycho-Relational Sphere of Patients: ProQoL

Prostate cancer and its treatment, particularly androgen deprivation therapy (ADT), can profoundly impact patients' quality of life. The aim of the prospective observational study reported here was to evaluate the effects of ADT on various aspects of quality of life in men with prostate cancer...

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Bibliographic Details
Published in:Oncology and therapy 2024-11
Main Authors: Cappuccio, Francesca, Buonerba, Carlo, Scafuri, Luca, Di Trolio, Rossella, Dolce, Pasquale, Trabucco, Serena Orsola, Erbetta, Filomena, Tulimieri, Elvira, Sciscio, Antonella, Ingenito, Concetta, Verde, Antonio, Di Lorenzo, Giuseppe
Format: Article
Language:English
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Summary:Prostate cancer and its treatment, particularly androgen deprivation therapy (ADT), can profoundly impact patients' quality of life. The aim of the prospective observational study reported here was to evaluate the effects of ADT on various aspects of quality of life in men with prostate cancer at a community-based hospital in Southern Italy. Eligible men initiating hormonal therapy were recruited between December 2021 and December 2023. Data were collected at baseline (T ) and after 3 months (T ) and 6 months (T ) of ADT using standardized questionnaires (European Organization for Research and Treatment of Cancer [EORTC] QLQ-C30, EORTC QLQ-PR25) and semi-structured interviews. Of the 52 participants, 43 completed all three assessments. The EORTC QLQ-C30 showed a statistically significant worsening in physical functioning (mean score decrease from 83.8 at T to 76.7 at T ; p 
ISSN:2366-1070
2366-1089
2366-1089
DOI:10.1007/s40487-024-00313-3