Biosensors for the detection of flaviviruses: A review

Flaviviruses affect the lives of millions of people in endemic regions and also have the potential to impact non-endemic areas. Factors such as climate change, global warming, deforestation, and increased travel and trade are linked to the spread of flaviviruses into new habitats and host species. G...

Full description

Saved in:
Bibliographic Details
Published in:Synthetic and systems biotechnology 2025, Vol.10 (1), p.194-206
Main Authors: Blázquez, Ana-Belén, Jiménez de Oya, Nereida
Format: Article
Language:English
Subjects:
Asymptomatic
Biosensors
Climate change
Deforestation
Dengue fever
Developing countries
Diagnostic
Diagnostic tests
Disease transmission
Encephalitis
Endemic species
Epidemics
Flaviviridae
Flaviviruses
Genomes
Global warming
Infections
LDCs
Meningitis
Microcephaly
Pathogens
Point-of-care testing (POCT)
Proteins
Reviews
RNA polymerase
Tropical diseases
Vaccines
West Nile virus
Zika virus
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Flaviviruses affect the lives of millions of people in endemic regions and also have the potential to impact non-endemic areas. Factors such as climate change, global warming, deforestation, and increased travel and trade are linked to the spread of flaviviruses into new habitats and host species. Given the absence of specific treatments and the limited availability of vaccines, it is imperative to understand the biology of flaviviruses and develop rapid and sensitive diagnostic tests. These measures are essential for preventing the transmission of these potentially life-threatening pathogens. Flavivirus infections are mainly diagnosed using conventional methods. However, these techniques present several drawbacks, including high expenses, time-consuming procedures, and the need for skilled professionals. The search for fast, easy-to-use, and affordable alternative techniques as a feasible solution for developing countries is leading to the search for new methods in the diagnosis of flaviviruses, such as biosensors. This review provides a comprehensive overview of different biosensor detection strategies for flaviviruses and describes recent advances in diagnostic technologies. Finally, we explore their future prospects and potential applications in pathogen detection. This review serves as a valuable resource to understand advances in ongoing research into new biosensor-based diagnostic methods for flaviviruses.
ISSN:2405-805X
2405-805X
DOI:10.1016/j.synbio.2024.10.005