Symptom experience of patients undergoing treatment for multiple myeloma: a longitudinal real-world electronic patient-reported outcomes study

Purpose Patients with multiple myeloma (MM) experience significant symptom burden. We used a symptom monitoring app to longitudinally characterize the MM treatment experience in detail based on line of therapy (LOT). Methods Adults with MM on active treatment completed weekly symptom monitoring surv...

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Bibliographic Details
Published in:Supportive care in cancer 2024-12, Vol.32 (12), p.802, Article 802
Main Authors: Patel, Mihir N., Nina, Anneli, Branchaud, Brenda, Herring, Kris W., Johnson, Suzanne, Scott, Julie, LeBlanc, Thomas W.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cancer therapies
Fatigue
Fatigue - epidemiology
Fatigue - etiology
Female
Humans
Longitudinal Studies
Male
Medicine
Medicine & Public Health
Middle Aged
Multiple myeloma
Multiple Myeloma - psychology
Multiple Myeloma - therapy
Muscle pain
Neurological disorders
Nursing
Nursing Research
Oncology
Pain Medicine
Patient Reported Outcome Measures
Quality of Life
Rehabilitation Medicine
Side effects
Surveys and Questionnaires
Symptom management
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Summary:Purpose Patients with multiple myeloma (MM) experience significant symptom burden. We used a symptom monitoring app to longitudinally characterize the MM treatment experience in detail based on line of therapy (LOT). Methods Adults with MM on active treatment completed weekly symptom monitoring surveys. Patients on their 4th LOT or greater were considered heavily pretreated. We characterized moderate to very severe (MOD-VS) symptom prevalence, weekly symptom burden, symptom bother (FACT-GP5), and health-related quality of life (HR-QoL) (EORTC QLQ-C30 Item 30) per LOT. Results We considered 109 patients on LOT 
ISSN:0941-4355
1433-7339
1433-7339
DOI:10.1007/s00520-024-08985-3