The Symbiotic Defence: Lung Microbiota and The Local Immune System

Microbiota defines all microorganisms that are vital for our immunological, hormonal, and metabolic homeostasis by living symbiotically in different parts of our body. On the other hand, the microbiome is a collection of microorganisms that can be detected together. The lungs are constantly exposed...

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Bibliographic Details
Published in:The New microbiologica 2024-11, Vol.47 (3), p.195
Main Authors: Yuruker, Ozel, Yılmaz, İskender, Güvenir, Meryem
Format: Article
Language:English
Subjects:
Airborne microorganisms
Animals
Bacteria - classification
Bacteria - isolation & purification
Homeostasis
Humans
Immune System
Immunology
Lung - immunology
Lung - microbiology
Lung diseases
Lung Diseases - immunology
Lung Diseases - microbiology
Microbiomes
Microbiota
Microorganisms
Respiratory tract
Respiratory tract diseases
Symbiosis
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Summary:Microbiota defines all microorganisms that are vital for our immunological, hormonal, and metabolic homeostasis by living symbiotically in different parts of our body. On the other hand, the microbiome is a collection of microorganisms that can be detected together. The lungs are constantly exposed to airborne microorganisms found in the upper respiratory tract. Until recently, the lower respiratory tract was considered sterile, as bacteria were rarely isolated from the lungs by conventional culture methods. Most chronic inflammatory lung diseases are caused by dysregulation of the lung microbiota, which has been discussed in many review papers. However, little is known whether microbiota dysymbiosis is a consequence or a cause of these diseases. In this review, we provide an overview of lung microbiota and lung immunity.
ISSN:1121-7138