Cu(II)-catalyzed synthesis of N -sulfonated quinolin-2(1 H )-one-3-carboxamides

Herein, N-N bond cleavage of sulfonylhydrazides was observed and applied in the synthesis of -sulfonated quinolin-2-(1 )-one-3-carboxamides. More than 30 examples were forged in 52%-97% yields. Further transformation delivered a 3,4-dihydro-quinolin-2(1 )-one derivative.

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2024-12, Vol.22 (47), p.9209-9213
Main Authors: Chen, Xue, Fang, Shi-Jie, Zhou, Quan, Huang, Wei, Liu, Qiu-Lan, Wang, Lei
Format: Article
Language:English
Subjects:
Chemical synthesis
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Summary:Herein, N-N bond cleavage of sulfonylhydrazides was observed and applied in the synthesis of -sulfonated quinolin-2-(1 )-one-3-carboxamides. More than 30 examples were forged in 52%-97% yields. Further transformation delivered a 3,4-dihydro-quinolin-2(1 )-one derivative.
ISSN:1477-0520
1477-0539
1477-0539
DOI:10.1039/d4ob01071j