Chiral sensing via dielectric waveguide-nanoparticle array interactions

Identifying the handedness of chiral materials in small quantities remains a significant challenge in biochemistry. Nanophotonic structures offer a promising solution by enhancing weak chiroptical responses through increased optical chirality. Utilizing a silicon-based approach for chiral sensing on...

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Bibliographic Details
Published in:Optics express 2024-11, Vol.32 (23), p.41390
Main Authors: Nouri, Hamed, Nader Askarpour, Amir, Dehkhoda, Parisa, Tavakoli, Ahad
Format: Article
Language:English
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Summary:Identifying the handedness of chiral materials in small quantities remains a significant challenge in biochemistry. Nanophotonic structures offer a promising solution by enhancing weak chiroptical responses through increased optical chirality. Utilizing a silicon-based approach for chiral sensing on a photonic integrated platform is highly desirable. In this study, we explore the interaction between a dielectric waveguide and silicon nanoparticles for detecting the handedness of chiral analytes. A chiral core induces polarization rotation of wavefields traveling along a dielectric waveguide with a square cross-section. This polarization rotation affects waveguide coupling differently depending on the left- or right-handed arrangement of nanoparticles around the waveguide, enabling enantiomer detection through discernible transmission differences. From a basic design to more practical structures, we investigate configurations that maintain the same working principles. Theoretical results based on the transfer matrix method corroborate the numerical simulations.
ISSN:1094-4087
1094-4087
DOI:10.1364/OE.538940