Liposomal topical drug administration surpasses alternative methods in glaucoma therapeutics: a novel paradigm for enhanced treatment

• Published in: Journal of pharmacy and pharmacology 2024-11
• Main Authors: Nordin, Nor Asyikin, Sadikan, Muhammad Zulfiqah, Lambuk, Lidawani, Hashim, Sabarisah, Airuddin, Syahira, Mohd Nasir, Nur-Azida, Mohamud, Rohimah, Ibrahim, Jamal, Kadir, Ramlah
• Format: Article
• Language: English
• ISSN: 0022-3573; 2042-7158; 2042-7158
• DOI: 10.1093/jpp/rgae129

Glaucoma is a leading cause of permanent blindness. Despite therapeutic advancements, glaucoma management remains challenging due to limitations of conventional drug delivery, primarily topical eye drops, resulting in suboptimal outcomes and a global surge in cases. To address these issues, liposomal drug delivery has emerged as a promising approach. This review explores the potential of liposomal-based medications, with a particular focus on topical administration as a superior alternative to enhance therapeutic efficacy and improve patient compliance compared to existing treatments. This writing delves into the therapeutic prospects of liposomal formulations across different administration routes, as evidenced by ongoing clinical trials. Additionally, critical aspects of liposomal production and market strategies are discussed herein. By overcoming ocular barriers and optimizing drug delivery, liposomal topical administration holds the key to significantly improving glaucoma treatment outcomes.